Jeffrey Makin was born in Wagga Wagga, NSW. In 1966 Makin completed a Diploma in Painting at the National Art School, Sydney. After graduating, he held his first exhibition at the Watters Gallery and received the Rockdale and Drummoyne Prizes. His development as an artist was inspired by various techniques, including traditional landscapes, modernism, impressionism and abstraction.
Makin is represented in all Australian national, state and most regional collections. These include the NGA, NGV, AGNSW, QAG, AGWA and Parliament House. In 2007 a boutique hotel in East Melbourne was named in his honour.